If you download profiles from the Internet, or if you copy them from another computer, then you should use the Install Profiles command (in the Noise Ninja menu) to ensure that the profiles can be located by the automatic profile loader.
When you select the Install Profiles command, it will display a directory browser. Navigate to the directory containing the profiles that you wish to install, and press the OK button. The directory and all subdirectories will be scanned for profiles. For each profile, the Manufacturer and Model annotations will be examined, and the profile will be saved in a location corresponding to those annotations.